Switched from Original and glad I did
Original helped a bit but stalled. The provider moved me to 2.0 and by month four the new growth looked noticeably cleaner. Still growing out but I'm wearing sandals again.
Onychomycosis
Toenail Fungus treatment reviews
What is toenail fungus?
Toenail fungus (onychomycosis) is a common fungal infection of the nail plate and nail bed. Because toenails grow slowly, any treatment — topical or oral — takes months before the nail looks clear. Vuret offers two prescription topicals: Vuret Original and Vuret 2.0.
Common signs
- Yellow, white or brown discoloration
- Thickened or crumbly nail
- Nail lifting from the bed
- Distorted nail shape
When to see a doctor in person
See a clinician in person if you have diabetes, poor circulation, pain, redness spreading to the skin, or signs of a bacterial infection.
Treatment options for toenail fungus
| Option | Overview |
|---|---|
| Over-the-counter topicals | Widely available; many people find they struggle to reach the nail bed through a thick nail. |
| Prescription topicals (e.g. Vuret Original, Vuret 2.0) | Applied daily for many months. Topicals generally avoid the systemic exposure of pills. |
| Oral antifungals | Prescription pills that may require liver function monitoring and have drug interaction considerations. |
| In-office procedures | Debridement or nail removal by a podiatrist for severe or painful cases. |
Vuret treatments for toenail fungus
What reviewers mention most
Share of reviews mentioning each theme.
Recent reviews
Slow, but the new growth is clear
I went in knowing it would take most of a year and that's exactly how it's played out. Around month three I could see a clear band at the base. Now about half the nail is normal. The pen is easy to use every night after a shower.
Good results, takes discipline
No smell, goes on easily, dries fast. Improvement is real and steady, though you do have to be consistent every single night. The free clipper set is a nice touch.
Year one done
Twelve months in. Two nails are clear, one still has a small patch at the tip that should grow out. I liked never having to go to an office or get labs.
Helpful guides
GuideHow to Get a Toenail Fungus Prescription OnlineRead guide →GuideToenail Fungus Treatment Without Pills or BloodworkRead guide →GuideLooking for a Jublia Alternative? Compounded Efinaconazole ExplainedRead guide →GuideHow Long Does Toenail Fungus Treatment Take? A Month-by-Month GuideRead guide →GuideWhy Over-the-Counter Toenail Fungus Treatments Often Don't WorkRead guide →GuideToenail Fungus Home Remedies: Vicks, Tea Tree Oil, Vinegar & ListerineRead guide →GuideHow to Keep Toenail Fungus From Coming BackRead guide →GuideHow to Track Toenail Fungus Progress With PhotosRead guide →GuideToenail Fungus Ingredients Explained: Terbinafine, Itraconazole, Efinaconazole, Ciclopirox & DMSORead guide →
Compare options
Frequently asked questions
How long does Vuret Original take to work?
Toenails grow slowly, so Vuret says most patients need 9–12 months of daily use for a fully grown-out nail. Some notice clearer new growth near the base around month 3.
What is in Vuret Original?
Itraconazole 1.5% and terbinafine 1.5%, two antifungals from different drug classes, in a base containing DMSO as a penetration enhancer.
How long does Vuret 2.0 take to work?
Vuret says visible improvement may begin in 3–6 months, with full clearance typically taking 9–12 months of consistent daily use.
What is in Vuret 2.0?
Efinaconazole 10% and ciclopirox olamine 8%, compounded in a licensed U.S. 503A pharmacy.
Sources
Product facts retrieved November 4, 2026.